Monoclonal Antibody Development
Why Precision Antibody?
Precision Antibody™ is a leader in custom monoclonal antibody development. For the past 7 years, we have been a boutique antibody developer for pharmaceutical, biotech, academic and federal laboratories. Our antibody team has strived to deliver successful projects to our customers in record time—40 to 60 days for standard monoclonal antibody projects. We are known for our personal service, speed, confidentiality, and our success-based guarantee.
Fill out our online quote for free estimate.
Types of Projects
Our monoclonal antibody service delivers on the most difficult projects. Our Precision Antibody™ team has developed custom monoclonal antibodies to targets including parasites, cancer-specific surface antigens, GPCRs, hormones, growth factors and their receptors, glycoproteins, peptides, proteins and their modification sites (mutation site-specific, phosphorylation site-specific, cleavage site-specific, etc), and other antigens such as small-molecule compounds and DNA. Specifically, we have been able to develop monoclonal antibodies for clients that recognize a single amino-acid mutation as well as antibodies that have a Kd as low as 1 x 10-12 M. We have created antibodies for various applications, such as functional assays, antibodies for immunoprecipitation, IHC, IF, flow cytometry, western blot, and EIA. Please talk to our experienced researchers regarding your project and application.
Monoclonal Antibody Packages
| Phase | Protocol | Package | ||
|---|---|---|---|---|
| Standard | Plus | Deluxe | ||
| Price | $8,500 | $10,000 | $12,000 | |
| Phase I | Initial Consultation: Antigen Selection, Design & Screening |  | | |
| Immunization of Mice | | | | |
| Serum screening by EIA | | | | |
| Email data to customer for evaluation & feedback | | | | |
| Fusion using mouse with highest specific antibody titer | | | | |
| Phase II | Cloning & Screening by EIA | | | |
| Data and Culture supernatant sent to customer for testing | | | | |
| Customer chooses up to 5 clones | | | | |
| Phase III | Production of purified antibodies - 1 x 10 mg (multiple clone package also available) | | | |
| Isotyping Immunoglobin for 1 Clone | | | ||
| Phase IV | Kd Determination for 1 Clone by Biacore | | ||
- Deliverables:
- Clones are chosen by the customer, Precision Antibody provides three vials of frozen cells per clone and 5 ml of culture supernatant.
- Standard Turnaround:
- 40 to 60 days.
- Precision Antibody Guarantee:
- Most antibody developers feel that developing one ELISA-positive antibody recognizing your antigen is sufficient for payment. At Precision Antibody™, we are only happy if we develop an antibody that meets your specific application. If we do not deliver at least one clone that works for your specific application, then we waive the phase II payment of $5,500. The phase II fee for screening and cloning is only paid upon success. Please note, before any project begins, customers must pay a start-up fee of $3,000, which is non-refundable.
- Volume & Collaboration Discount:
- Our Precision Antibody team is very interested in projects where reagents rights might be exchanged for discounted pricing. Additionally, Precision Antibody does give volume discounts, please enquire about both of these programs with Dr. Jun Hayashi, V.P. of Precision Antibody at 410-884-4100.
Precision Antibody’s Success
It is never TOO EARLY to start planning for antibody development. A carefully planned antibody development strategy almost always provides good results. Before you start antigen preparation, you must have a well-defined screening strategy in place. Please start talking to us when you anticipate the need for developing antibodies to your target. We strive to work with you to develop the reagent you need. We provide personal attention to each custom antibody project. A mere development of antibodies that recognize the antigen is not sufficient. Successful development of antibody reagent that meets your application is our goal and we measure our success attaining that goal. We pride ourselves on having a success rate of over 90% for our projects. Please feel free to contact us with your specific project.
To contact our staff for your next antibody project:
Call us at 410-884-4100, email orders@precisionantibody.com, or try our online quote request form. We provide free consultation and an exact price quote for all antibody projects.