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Custom Polyclonal Antibodies

Rat And Mouse Polyclonal Antibody Development Service

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Why Choose Precision Antibody?

Accreditation

Scientists at our Research and Development (R&D) department are continually improving our state-of-the-art proprietary technology to achieve cost effective development of quality antibodies to serve you better. All of the development processes are performed at our Columbia, Maryland facility, and we do not out-source our work outside the United States as many of our competitors offering budget price do. Your work remains confidential and all the products we generate belong to you. We are AAALAC and OLAW accredited.

Previous Projects

Our Precision Antibody™ team has developed custom monoclonal antibodies used for many applications such as:

  • Receptor and/or ligand neutralization.
  • Receptor internalization (for ADC applications).
  • Receptor agonistic antibodies.
  • Anti-idiotypic antibodies for PK and ADA studies.
  • Antibodies for sandwich ELISA and lateral flow applications.
  • Modification site-specific antibodies (mutation site-specific, phosphorylation site-specific, cleavage site-specific, etc.) High affinity antibodies for immune-mass spec (Immuno-MRM) applications.
  • Conformation-specific antibodies.
  • Antibodies against small molecule drugs, carbohydrates, lipids, and nucleic acids.
  • Antibodies for immunoprecipitation, IHC, IF, flow cytometry, western blot, and EIA.

Our track records and credentials

We are the preferred service provider for major global pharmaceutical and biotechnology companies. We also provide BPA for NIH researchers. We are recognized by government agencies as quality antibody developer that provides comprehensive service as evident from our track record for being selected as antibody development contractor for the following initiatives:

  • Leidos / NCI Clinical for Proteomic Technologies for Cancer (CPTC): Development gold standard mAbs for cancer biomarkers.
  • Leidos / NCI Clinical for Proteomic Technologies for Cancer (CPTC): Antibody & antigen characterization by Biacore™ Analysis Service, ELISA, Western blot analyses, isotyping, & antigen characterization by SDS-PAGE.
  • NIAID Malaria Vaccine Production and Support Services contract administered by Leidos.
  • Blanket Purchase Agreement (HHSN263201000041B) for NIH Researchers for:  (1) Custom Monoclonal/Polyclonal Antibody Development (2) Small and Large Scale Antibody Production, and (3) Biacore Analysis Service.
  • National Center for Advancing Translational Sciences (NCATS): Reagent generation for bioanalytical method development for biologics.

Custom Polyclonal Antibodies

Rat and mouse polyclonal antibody development service:

At times you may encounter the situation “I needed that antibody, yesterday!!” Well, PA cannot reverse the time to accommodate your needs, but we offer the next best option and develop high-affinity hyperimmune serum in less than 3 weeks using mice or rats. Affinity purification will add additional 7-10 days. The development of rat polyclonal antibody is the most popular option for many of our customers. Due to the high specific IgG titer we achieve, even a smaller amount of serum goes a long way in your research.

Rabbit polyclonal antibody development service:

PA offers traditional rabbit polyclonal antibody development service. We have 60 or 90-day protocols and continuous production of antibody is possible.We also offer antibody purification services from rabbit polyclonal serum. (see Antibody Production and Purification section)

Please contact our specialist for rabbit polyclonal service.
For immunization of larger animals, please inquire.

Cell Banking Services