COLUMBIA, Maryland, August 31, 2020: A&G Pharmaceutical, Inc (A&G), with its Custom Antibody Division Precision Antibody has developed mouse monoclonal antibodies (mAbs) against COVID-19 antigens; Spike protein S1 and nucleocapsid protein (N-protein).
Anti-SARS-Cov2 S1 protein (non RBD) mAbs:
- Available antibodies recognize the S1 protein outside of the RBD region.
- COVID-19-specific (SARS-Cov2) and do not cross-react to SARS Cov1 (SARS Cov 2003) and MERS.
- Recognize the trimeric form of Cov-2 S1 protein similarly or better than the S1 monomer.
- Our anti-S1 and anti-RBD antibodies bind with high affinity to non-overlapping epitopes*, making them compatible with sandwich ELISA or lateral flow applications.
- Several selected antibodies can be used on Protein Simple Wes, on Western blot and for immunoprecipitation.
Anti-SARS-Cov2 RBD protein mAbs:
- Available antibodies recognize the RBD region of the S1 proteinmAbs are COVID-19-specific (SARS-Cov2) and do not cross-react to SARS Cov1 (SARS Cov 2003) and MERS.
- Recognize the trimeric form of Cov-2 S1 protein similarly or better than the S1 monomer.
- Our anti-RBD antibodies bind with high affinity to non-overlapping epitopes*, making them compatible with sandwich ELISA or lateral flow applications.
- Several selected antibodies can be used on Protein Simple Wes, on Western blot and for immunoprecipitation.
Anti-SARS-Cov2 nucleocapsid protein mAbs:
Selected antibodies have the following properties
- All selected antibodies bind equally well in the presence of 1% Triton X100
- Our anti-N protein antibodies bind with high affinity to non-overlapping epitopes*, making them compatible with sandwich ELISA or lateral flow applications.
- Selected antibodies can be used on Protein Simple Wes, on Western blot and for immunoprecipitation.
*As determined by Scouting and Epitope binning assays
Our Anti-Human ACE2 protein mAbs:
- Selected antibodies can be used on sandwich EIA Western blot and for immunoprecipitation.
All the Anti-S1 protein, Anti-RBD, Anti-N protein, and Anti-Human ACE2 Protein mAbs are available for purchase at store.precisionantibody.com/antibodies
Precision Antibody has also developed Neutralizing mouse Monoclonal Antibodies and Fully Human monoclonal Antibodies against Sars-CoV-2. For more information about our Neutralizing mAbs and our Fully Human Covid-19 mAbs, please contact Dr. Jun Hayashi (jhayashi@precisionantibody.com)
For any inquiries about the catalog antibodies or another potential custom antibody projects, please contact:
Keenan Doubleday
Sales Manager, Precision Antibody
kdoubleday@precisionantibody.com
Sarah Hayashi
Project Manager, Precision Antibody
shayashi@precisionantibody.com
