Every custom antibody development project is unique. Precision Antibody will sit with you and design the project that delivers antibodies that meets your specific needs. You will receive our attentive understanding of your goals, our expert recommendations, and the highest quality service. Our goal is your success.
Design Your Project
Every antibody development project is unique and understanding of biology behind each project is important. Precision Antibody scientists have vast scientific background in immunology, cell biology, molecular biology, biochemistry and cancer biology.
A carefully planned, well-defined antibody development strategy almost always provides good results. Your project starts with an in-depth discussion with detailed attention to your needs between the PI and our scientists. Particular attention will be given to your intended assay so that we can help you choose appropriate immunogen and screening strategies. Scientists at our R&D department are continually improving our state-of-the-art proprietary technology to achieve cost-effective development of quality antibodies to serve you better.
We pride ourselves on having a success rate of over 95% delivering the antibodies that work in your intended applications.
Our Process
Here is a typical segment of our monoclonal antibody development project:
1. Tell us your goal |
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2. Finalize the Plan |
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3. Optimize Your Antigen to Meet Your Goals |
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4. Find and Execute the Best Immunization Strategy Precision Antibody’s proprietary immunization technology is designed to be tailored to your project. All variables are considered to assure we can obtain the best titer in a short amount of time (1:100,000 in 2 ½ weeks) which guarantees the best antibody. PA also offers specialized immunization strategies for cell based immunizations and other challenging targets. |
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5. Optimized Process for Hybridoma Generation and Screening |
PA will send you data at each milestone (Phase) to keep you up-to-date. we will guide you through the next phases that will lead you to the selection of best hybridoma(s) for your application. This may include Octet based binding affinity measurements, Protein Simple WES assay, and flow-based functional assays. Please view our full list of our services.
PA has experience making antibodies against vastly different targets that work in the intended applications:
Target Molecules |
Small molecules, carbohydrates, nucleic acids, lipids, synthetic polymers, peptides, proteins, receptors (single and multi-transmembrane), glycotopes, bacterial and viral components, fungal components, allergens |
Structural Moieties | Cleavage site-specific antibodies Antibodies against conformational epitopes Post transcriptional modification site-specific antibodies Mutation site-specific antibodies Anti-idiotypic antibodies |
Applications |
Antibodies for PK studies (Anti-idiotypes) |
Functional Antibodies |
Neutralizing antibodies |
Assays | Potency assays Stability assays (real time & accelerated) Internalization assays Cell-line Expression Profiling Immunohistochemistry (IHC) |