Precision Antibody™ also has an AAALAC accredited animal facility for ascites production. Occasionally, we encounter hybridoma cells that do not produce monoclonal antibodies in in vitro systems. Ascites production can be achieved using nude mice/rats or syngeneic host mice as an alternative method to produce such monoclonal antibodies. Ascites production often yields higher concentrations of monoclonal antibody. We prefer to use nude athymic mice for ascites production to eliminate the contamination of endogenous mouse IgG